AbbVie Scientist, II in Redwood City, California


Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products — Imbruvica, Venclexta, and Empliciti — and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments.

AbbVie is seeking a confident, proactive and experienced Scientist II to join our Immuno-Oncology team. The successful candidate will participate in projects discovering and defining the mechanism of action of novel drugs using both anti-mouse tool reagents as well as anti-human lead candidate molecules. The role will include troubleshooting assays, designing novel approaches, organizing and analyzing data, and participation in group and departmental meetings. The team is highly collaborative and the successful candidate will be able to manage contributions to many projects in distinct research areas. In vitro and ex vivo assays utilizing both mouse cells and human cell-based in vitro assays will be required. Background in flow cytometry, cytokine analysis, in vitro proliferation assays, and other common cell biology and immunological laboratory assays is required. Knowledge and experience with current technologies for support of in vitro assays is highly desirable. A strong background in immunology is preferred.

The successful candidate will be a technical expert that will independently investigate, identify, develop and optimize new methods and techniques to address critical project needs. Reading and adapting the primary literature to accomplish assignments is expected. Demonstrated mastery of broad range of experimental techniques and methods of data analysis are expected.

Key Responsibilities Include:

  • Independently design, execute and interpret critical experiments to answer scientific questions.

  • Understand the broad objectives of the project as well as their role in achieving those objectives, and modify experimental plan when required, to respond.

  • Learn, understand and master new experimental techniques and act as a resource or mentor for others.

  • Innovate and implement new experimental protocols.

  • Effectively organize and present scientific plans and data at lab meetings and departmental scientific meetings.

  • Contribute to writing and conceptual framework of publications, presentations and patents.

  • Routinely read and apply relevant scientific literature.



  • BS and equivalent education with typically 7 or more years of experience, or MS or equivalent education with 5 or more years of experience.
  • Demonstrated ability to independently design, execute and interpret critical experiments to answer scientific questions.
  • Ability to work collaboratively within and outside of his/her immediate project team.
  • Proficiency in standard immunological techniques such as ELISA, Multiplex assays, ELIspot, primary cell culture, cell subset isolation, and advanced flow cytometry techniques is required.
  • Demonstrated ability to learn, understand and execute new experimental techniques.
  • Ability to multi-task and work within timelines.
  • Demonstrated scientific writing skills and strong verbal communication skills.

Job Classification: Experienced
Primary Location: USA-California-Redwood City
Organization: Research & Development
Schedule: Full-time
Shift: Day
Travel: Yes, 5 % of the Time
Req ID: 1703974

Equal Opportunity Employer Minorities/Women/Veterans/Disabled